24 months after treatment, the overall efficacy rate using loose criteria was 91.0% in the BrF group and 90.4% in the BrRCS group (p= 0.0003). Clinical study results (Clinicaltrial.gov/NCT04757753) currently under peer review.

Ng, Y.-L., Mann, V., Rahbaran, S., Lewsey, J., & Gulabivala, K. (2007). Outcome of primary root canal treatment: Systematic review of the literature – Part 1. Effects of study characteristics on probability of success. International Endodontic Journal, 40, 921–939.

Ng, Y.-L., Mann, V., & Gulabivala, K. (2008). Outcome of secondary root canal treatment: A systematic review of the literature. International Endodontic Journal, 41(12), 1026–1046.

Loose criteria evaluation (Clinicaltrials.gov). Strict criteria evaluation at 24 months post-treatment, the overall success rate was 86.6% in the BioRoot Flow group and 87.7% in the BioRoot™ RCS group (non-inferiority demonstrated; p = .0195) (Simon S and Al. Clinical efficacy of root canal treatment at 2 years using a new ready-to- use injectable calcium silicate-based sealer: A multicentric randomised controlled trial. Int Endod J. 2025;00:1–1).