BioRoot™ Flow: is a medical device intended for permanent root canal filling material in combination with gutta-percha points in case of inflamed or necrotic pulp or following a retreatment procedure. Manufactured by Septodont, France. CE marked (CE 2797) Class III implantable. GenENDO is part of the endodontic treatment to prepare the root canal. Both can be used together or separately in endodontic procedures.

Giulio GAVINI, Marcelo dos SANTOS, Celso Luis CALDEIRA, Manoel Eduardo de Lima, MACHADO, Laila Gonzales FREIRE, Elaine Faga IGLECIAS, Ove Andrea PETERS, George Táccio de Miranda, CANDEIRO. Critical Review Endodontic Therapy – Nickel–titanium instruments in endodontics: a concise review of the state of the art PHILLIP L Tomson, Stéphane R Simon – Contemporary cleaning and shaping of the root canal system – Prim Dent J. 2016;5(2): 46-53.​

Loose criteria evaluation (Clinicaltrials.gov). Strict criteria evaluation at 24 months post-treatment, the overall success rate was 86.6% in the BioRoot Flow group and 87.7% in the BioRoot™ RCS group (non-inferiority demonstrated; p = .0195) (Simon S and Al. Clinical efficacy of root canal treatment at 2 years using a new ready-to- use injectable calcium silicate-based sealer: A multicentric randomised controlled trial. Int Endod J. 2025;00:1–